Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 40-75 years; 2. Knee osteoarthritis patients scheduled for total knee arthroplasty; 3. Knee pain > 3 months; 4. BMI < 35.
Exclusion criteria
Exclusion criteria: 1. History of arthroplasty in the lower limb; 2. History of injury and surgery in the past 6 months; 3. Receiving muscle strengthening or physical therapy in the past 6 months; 4. Other diseases that cause knee pain (such as rheumatoid arthritis, gout, etc.); 5. Other diseases that cause pain or dysfunction of the lower limbs (lumbar disc herniation, Parkinson's, Alzheimer's, etc.); 6. Unable to walk short distances independently (walking distance less than 100m); 7. Severe cognitive impairment and communication disorders; 8. Knee valgus deformity >= 15°.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| KOOS score;the ratio of medial/lateral knee contact force; | — |
Secondary
| Measure | Time frame |
|---|---|
| inflammation;Quadriceps isokinetic strength;Active knee range of motion;knee pain;Timed-up-and-go test;gait speed;5-times Sit-to-stand test;Intention to surgery;Proprioceptive test;Balance test; | — |
Countries
China
Contacts
West China Hospital, Sichuan University