depressive disorder
Conditions
Interventions
Depression group:Conventional drug therapy plus 2mA transcranial direct current stimulation for 30 minutes daily, for a duration of 4 weeks, 5 times per week, totaling 20 sessions.
Healthy control:Conventional medical treatment only.
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
14 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1.The patient meets the diagnostic criteria for depression according to the International Classification of Diseases (ICD-10); 2.The patient is experiencing the first episode of depression, or has not used antidepressants, mood stabilizers, or antipsychotic medications for the two weeks prior to treatment initiation; 3.The Hamilton Depression Rating Scale score is greater than 20; 4.The patient is aged between 13 and 35 years, with no gender restriction; 5.The patient is right-handed; 6.The patient has no history of substance abuse or alcohol dependence; 7.The patient's condition and vital signs are stable, with no other severe complications such as respiratory failure, heart failure, or pulmonary infection; 8.The patient has signed an informed consent form prior to undergoing transcranial direct current stimulation (tDCS) therapy and voluntarily participates in this study.
Exclusion criteria
Exclusion criteria: 1.Presence of suicidal ideation, diagnosis of bipolar affective disorder; 2.Comorbid with other psychiatric disorders, cranial trauma; 3.History of previous epileptic seizures or unexplained loss of consciousness; 4.Currently participating in other clinical trials; 5.Undergoing other non-invasive neurostimulation, magnetic stimulation, or similar neuromodulation therapies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Near-infrared brain imaging examination;SDS; | — |
Countries
China
Contacts
Public ContactYujun Li
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed