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The role and mechanism of PCMS in post-acquired brain injury motor recovery

The role and mechanism of PCMS in post-acquired brain injury motor recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088113
Enrollment
Unknown
Registered
2024-08-12
Start date
2024-08-30
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acquired brain injury

Interventions

peripheral nerve stimulation:peripheral nerve stimulation
paired cortex-spinal motor neuron stimulation:paired cortex-spinal motor neuron stimulation
paired associated stimulation:paired associated stimulation

Sponsors

Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The first onset of stroke, confirmed by clinical and imaging examinations (including hemorrhagic and ischemic); 2. Age 18-75y, 1-6 months after onset, stable; 3. The hemiplegic upper limb was assessed by the scale to be in Brunnstrom II-III; 4. Have ipsilateral resting or active MEP; 5. Willing to sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Unstaital signs; 2. participation in other clinical trials 3. Having aphasia, cognitive and mental disorders,unable to complete instructions as instructed by the author; 4. Having metallic implants or incomplete skull or cranioplasty; 5. Existence of peripheral nerve or muscle injuries and diseases in the upper limbs; 6. Skin soft tissue infection or allergy at the site of electromyographic electrode adhesion; 7. Individuals with upper limb fractures, dislocations, joint stiffness, ectopic ossification, pain, etc. that affect upper limb joint movement; 8. mamaligmalignant tumor; 9. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer scale;the conduction efficiency between cortex and spinal motor neuron with motor evoked potential;

Secondary

MeasureTime frame
Brunnstrom scale;wireless Gyro-sensor;Ashworth scale;Surface Electromyography;the excitability of motor cortex with Electroencephalogram;the excitability of spinal motor neuron with F-wave;

Countries

China

Contacts

Public ContactLiu Gang

Huashan Hospital Affiliated to Fudan University

062105208@fudan.edu.cn+86 181 1745 9259

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026