Postoperative delirium and cognitive function
Conditions
Interventions
Noise isolation group:BIZOE noise-cancelling headphones were used for noise isolation during surgery
Blank control group:none
Sponsors
Fujian Cancer Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: age > 65 years old, gender unlimited; Preoperative American society of anesthesiologists (ASA) grade I to III; Laparoscopic surgery for gastrointestinal malignancies under general anesthesia is planned; Estimated operation time > 3 hours; Patients who can correctly understand the trial process and evaluate the use of various scales, and have sufficient cognitive ability to complete the scales; Informed consent of the patient or legal representative.
Exclusion criteria
Exclusion criteria: Patients with a history of neuropsychiatric disease and cognitive dysfunction; A history of chronic narcotic drug use or alcohol abuse; Patients with hearing impairment; Requiring emergency surgery due to comorbidities (bleeding, perforation, obstruction); Known significant liver disease (Child-Pugh score B or C or presence of ascites); Renal failure (serum creatinine level =1.5 mg/dL); Obvious heart disease (ejection fraction < 50%); Significant chronic obstructive pulmonary disease (forced expiratory volume in 1 second or carbon monoxide dispersion < 50% of the expected value); Patients who are unable to communicate due to language barriers; Patients and legal representatives refuse to participate in clinical trials; Other circumstances in which the investigator determines that the subject is not suitable for participation in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of postoperative delirium;Cognitive function;Postoperative recovery quality;Area under the curve of pain scores during exercise and at rest 0-72 hours after surgery;PCIA was first used after surgery as a time to press for remedial analgesia;The total amount of opioid relief analgesics converted to morphine 0-72 hours after surgery; | — |
Countries
China
Contacts
Public ContactXuru Zhang
Fujian Cancer Hospital
Outcome results
None listed