Study on the effect of transcranial ultrasound stimulation based on near infrared imaging technology combined with lower limb rehabilitation robot on lower limb function and neural mechanism of stroke patients

Study on the effect of transcranial ultrasound stimulation based on near infrared imaging technology combined with lower limb rehabilitation robot on lower limb function and neural mechanism of stroke patients - Effect of transcranial ultrasound stimulation combined with lower limb rehabilitation robot on lower limb function in stroke patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400088089

Enrollment

Unknown

Registered

2024-08-12

Start date

2024-08-12

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Control group:Routine rehabilitation combined with lower limb exoskeleton rehabilitation robot group

Experimental group:Transcranial ultrasound combined with lower limb exoskeleton rehabilitation robot group

Eligibility

Sex/Gender

All

Age

45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with first-onset ischemic stroke who meet the "2014 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke" issued in 2015 and confirmed by head CT or MRI imaging scans; 2. The course of the disease was =1 month, the disease was stable, and the lesion was located in one cerebral hemisphere (cortex and subcortex); 3. Age 45-70 years old; 4. Brunnstrom? stage and above of the affected lower extremity; 5. Clear consciousness, stable vital signs, can cooperate well with training; 6. Willing to sign the informed consent for this study.

Exclusion criteria

Exclusion criteria: 1. Accompanied by consciousness disorders or cognitive dysfunction, mental disorders and mixed aphasia and other impact assessment and treatment; 2. Accompanied by cerebral hemorrhage; 3. Serious dysfunction of liver, kidney, heart and other important organs; 4. Existing musculoskeletal diseases affecting lower limb mobility disorders; 5. Built-in cardiac pacemaker or other metal medical devices implanted in the brain; 6. Improved Ashworth muscle tone of affected lower extremity = grade 3; 7. Any condition that the investigator believes is detrimental to the subject or prevents the subject from meeting or performing the study requirements. 8. Refusing to sign informed consent

Design outcomes

Primary

Measure	Time frame
Fugl-Meyer motor function assessment–lower extremity,FMA-LE;Berg balance scale, BBS;	—

Secondary

Measure	Time frame
Functional near-infrared spectroscopy, fNIRS;Functional ambulation category, FAC;	—

Countries

China

Contacts

Public ContactHongfei Qiao

The Second Affiliated Hospital of Xi 'an Jiaotong University

66725578@qq.com+86 186 0298 0099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026