Bortezomib associated peripheral neuropathy
Conditions
Interventions
control group:chemotherapeutics + Micobor
treatment group:chemotherapeutics + Micobao + Gui Zhi Fu Ling
Sponsors
The Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?meet the diagnostic criteria of active multiple myeloma;? Chinese medicine diagnosis meets the type of cold-congealed blood stasis;? Symptoms of peripheral neuropathy , NCI-CTCAE grade 1 or higher; ?conscious at baseline state, without memory, comprehension and attention disorders; ? not participating in other clinical studies; ?age greater than 18 years old.
Exclusion criteria
Exclusion criteria: ? can appear M protein, fracture or other diseases of neuropathy; ? Smoking myeloma; ? People with severe cognitive impairment who are unable to communicate; 4. Participate in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nerve conduction velocity;visual analogue scales ;Classification of peripheral neuropathy;FACT/GOG-Ntx Neurotoxicity Assessment Tool Scale score;chinese medicine syndrome scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| MBD classification;visual analogue scales of bone pain; | — |
Countries
China
Contacts
Public ContactXing Cui
The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed