Postoperative pain
Conditions
Interventions
Ropivacaine group (group R):Local anesthetic liquid configuration: 40ml solution (containing 0.375% ropivacaine)
Intravenous infusion solution: 20ml of normal saline
Dexmedetomidine as a ropivacaine adjuvant group (group RD):Local anesthetic liquid configuration: 40ml solution (containing 0.375% ropivacaine + 1 µg/kg dexmedetomidine)
Intravenous infusion solution:
Dexmedetomidine intravenous infusion combined ropivacaine group (group RDiv):Local anesthetic solution: 40ml solution (containing 0.375% ropivacaine)
Intravenous infusion solution: 20ml normal saline
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age: 18-65 years old; (2) elective thoracoscopic surgery; (3) ASAI.~ III
Exclusion criteria
Exclusion criteria: (1) Contraindications to regional nerve blocks, including skin infections or bleeding disorders at the site of the block; (2) Those who are allergic to any of the drugs used in this trial; (3) Bradycardia (HR<50 times/min); (4) Patients with severe cardiovascular and cerebrovascular diseases, respiratory diseases, and abnormal liver and kidney function before surgery; (5) History of chronic pain, long-term use of opioids, hormones or non-steroidal drugs; (6) Inability to communicate normally: hearing impairment, language comprehension impairment, mental illness, etc.;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS score;Total opioid consumption of PCIA after surgery;Remedial analgesia;Postoperative recovery index;Ramsay rating;QoR-15 rating;Patient satisfaction;Intraoperative opioid dosage;The occurrence of intraoperative adverse reactions;PACU recovery;Postoperative complications; | — |
Countries
China
Contacts
Public ContactLinlin Zhao
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed