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Study on the therapeutic effect and safety of modified Changpu Yujin Tang in the treatment of Convulsive status epilepticus

Study on the therapeutic effect and safety of modified Changpu Yujin Tang in the treatment of Convulsive status epilepticus

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088043
Enrollment
Unknown
Registered
2024-08-09
Start date
2024-06-29
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Convulsive status epilepticus

Interventions

experimental group:Standardized treatment for status epilepticus + modified Changpu Yujin Tang
control group:Standardized treatment for status epilepticus

Sponsors

Tianjin Huanhu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: a. Meets the diagnostic criteria for CSE proposed by 2015 ILAE: generalized tonic clonic seizures lasting for more than 5 minutes or recurrent, with incomplete recovery of consciousness during the interval between episodes; Or focal attacks with consciousness disorders lasting for more than 10 minutes; b. Age = 18 years old; c. Gender unlimited; d. Sign an informed consent form.

Exclusion criteria

Exclusion criteria: a. Non convulsive status epilepticus; b. Pseudo seizure duration similar to epileptic seizures, cerebrovascular diseases, severe brainstem injury induced enucleated tonic state, syncope seizures, mental disorders, etc; c. Individuals with severe heart, lung, and kidney dysfunction, or those with autoimmune, chronic infectious, or hematological diseases; d. Women who are pregnant, breastfeeding, or have a pregnancy plan in the next three months; e. Individuals with a history of alcohol or other drug addiction or abuse; f. Simultaneously receiving clinical observations of other drugs.

Design outcomes

Primary

MeasureTime frame
Ending time of Convulsive status epilepticus;

Secondary

MeasureTime frame
mSTESS;Todd's paralysis incidence rate;The incidence of refractory status epilepticus;The incidence of super refractory status epilepticus;

Countries

China

Contacts

Public ContactYue Wei

Tianjin Huanhu Hospital

yuewei2008@163.com+86 137 5268 6958

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026