Pain
Conditions
Interventions
Ropivacaine group (Group L):Group L received conventional ropivacaine nerve block anesthesia combined with general anesthesia
Esketamine Group (Group I):Group I used ketamine combined with ropivacaine nerve block anesthesia combined with general anesthesia
Sponsors
Xuzhou Renren Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: BMI 18.5-35.0 kg/m2, age 18-60 years old, ASA II-III, orthopedic surgery under quasi-general anesthesia;
Exclusion criteria
Exclusion criteria: Age younger than 18 years, patient who has not quit smoking, pneumothorax or giant bullosa, history of pulmonary surgery, invasive mechanical ventilation within 30 days, pregnancy, persistent hemodynamic instability or refractory shock, severe heart disease, severe chronic obstructive pulmonary disease, moderate or severe pulmonary hypertension, moderate or severe acute respiratory distress syndrome, diagnosis of intracranial hypertension, patient participating in it other interventional studies, local anesthetic allergy, puncture site infection or coagulation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scoring;Pittsburgh Sleep Quality Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative adverse reactions;Postoperative QoR-40 score;Intraoperative propofol and remifentanil dosages; | — |
Countries
China
Contacts
Public ContactWang Kang
Xuzhou Renren Hospital
Outcome results
None listed