Caesarean section
Conditions
Interventions
Liposomal bupivacaine group:Each side was given 0.665% liposomal bupivacaine, i.e. 133mg liposomal bupivacaine diluted to 20ml with normal saline.
Ropivacaine group:Each side was given 0.375% ropivacaine (75mg/20ml).
Sponsors
the First Hospital of Lanzhou University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old; 2. Full-term pregnancy (37-42 weeks); 3. American Anesthesiologist Rating (ASA) I-III; Body mass index (BMI) 18-30kg /m2; 4. Patients with cesarean section operation under spinal anesthesia; 5.Be able to understand the research process and methodology and participate in the study voluntarily
Exclusion criteria
Exclusion criteria: 1. Refuse to sign the informed consent; 2. Those who have anesthesia contraindications or have had anesthesia accidents in the past; 3. Patients with known or suspected allergy to the investigational drug and family history; 4. People with severe mental illness, unable to cooperate, heart insufficiency, liver and kidney dysfunction; 5. Insufficient analgesia occurred during the operation, which required remedial analgesia; 6. Refuse to use intravenous pain relief pumps; 7. Patients with any other factors deemed unsuitable for participation in this trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference of Numeric Rating Scale pain scores at rest and during exercise within 24h after anesthesia;Differences in the number of Patient controlled analgesia (PCA) compressions between patients within 24h after anesthesia; | — |
Countries
China
Contacts
Public ContactHan Fangfang
the First Hospital of Lanzhou University
Outcome results
None listed