Abdominal Surgery Diseases
Conditions
Interventions
dexmedetomidine group:Intraoperative continuous intravenous dexmedetomidine
control group:Intraoperative continuous intravenous saline
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Age
3 Years to 13 Years
Inclusion criteria
Inclusion criteria: 1. General surgical procedures such as choledochal cystectomy, Rex surgery and abdominal surgeries 2. ASA grade ?-III 3. Estimated anesthesia time is more than 3h 4. Informed consent of the family/patient and willingness to cooperate with follow-up visits.
Exclusion criteria
Exclusion criteria: 1. patients with a history of surgery within 1 month 2. Patients with contraindications to the use of dexmedetomidine; 3. patients with disorders of uric acid metabolism (e.g., gout) 4. Patients with neurocognitive dysfunction (e.g. trisomy 21);Patients with severe hepatic and renal dysfunction, cardiopulmonary, cerebrovascular diseases and psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative postoperative behavioral changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative deilirium;Blood biochemical indicators;postoperative pain;Intraoperative vital signs; | — |
Countries
China
Contacts
Public ContactShe ying Jun
Guangzhou Women and Children's Medical Center
Outcome results
None listed