craniotomy(TBI)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: For patients admitted to hospital for acute traumatic brain injury and undergoing surgery, head CT and MRI examinations included subdural hematoma, epidural hematoma, and intracerebral hematoma (including diffuse axonal injury and brain stem injury). The surgical methods were craniotomy hematoma removal combined with decompressive craniotomy. Inclusion criteria: age 25-78 years old; No gender limitation; Glasgow Coma Scale (GCS) score 3-12 at admission; The incision was unilateral and the operation time was less than 6 h. Medical records are complete.
Exclusion criteria
Exclusion criteria: Patients with open skull defect; Intracranial tumor or aneurysm; Combined with serious injury to other organs or organs; Vital signs were unstable upon admission; History of local anesthetic allergy; Puncture site infection or damage; Previous uncontrolled hypertension and diabetes; Cardiomyopathy or persistent arrhythmia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early postoperative neurological complications;Intraoperative dosage of remifentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics;Hemodynamic parameters of middle cerebral artery;Intraoperative dosage of propofol;Intraoperative hypertension, tachycardia and other events;Utilization rate of vasoactive drugs;Intracranial pressure levels;Recovery breathing time after surgery;Incidence of postoperative coughing, convulsions, and agitation;Serum levels of cerebral nerve injury related indicators;Cerebral oxygen supply and demand balance index;Stress response index;Oxidative stress response index;Index of renal injury; | — |
Countries
China
Contacts
the Traditional Chinese Medicine Hospital of Kunshan