Study on the relationship between peripheral and central inflammation and nerve injury markers in patients with mild cognitive impairment

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400087968

Enrollment

Unknown

Registered

2024-08-08

Start date

2024-02-01

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Mild cognitive impairment group :None

Normal control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age = 18, < 90; 2. Elective surgery should be performed under combined spinal-epidural anesthesia; 3. ASA I~III level; 4. All patients or their families sign informed consent forms.

Exclusion criteria

Exclusion criteria: Unable to communicate due to coma, severe dementia or language disorder before operation.

Design outcomes

Primary

Measure	Time frame
Cognitive function;	—

Secondary

Measure	Time frame
IL-6;TNF-a;IL-1ß;IL-4;IL-10;Glial fibrillary acidic protein, GFAP;Neurofilament light, NFL;	—

Countries

China

Contacts

Public ContactJi Muhuo

The Second Affiliated Hospital of Nanjing Medical University

jimuhuo2009@sina.com+86 159 9623 5006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026