systemic lupus erythematosus
Conditions
Interventions
Non-carotid intima thickening group:None
Carotid intima thickening group:None
Carotid plaque group:None
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: All patients met the following requirements: 1. Meeting the diagnostic criteria for systemic lupus erythematosus revised by the American College of Rheumatology in 1997, meeting 4 or more criteria to diagnose systemic lupus erythematous 2. All subjects were female, =18 years old, < 65 years old, regardless of ethnicity or region.
Exclusion criteria
Exclusion criteria: Patients with one or more of the following conditions were excluded: 1. Previous history of coronary heart disease, stroke and other cardiovascular and cerebrovascular diseases; 2. Combined with other autoimmune diseases other than systemic lupus erythematosus; 3. Pregnant or lactating women; 4. Combined with serious infection, malignant tumor and other diseases; 5. Patients receiving folic acid therapy within the last 12 weeks; 6. Lack of stroke screening data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homocysteine;Carotid Intima-media Thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Triglyceride;Total Cholesterol;High-Density Lipoprotein Cholesterol;Low-Density Lipoprotein Cholesterol;C-reactive Protein;Erythrocyte Sedimentation Rate;Alanine Transaminase;Aspartate Transaminase;C3;C4;ANA;dsDNA;aPLs;leukocyte;Platelet;Hemoglobin;Neutrophils;Lymphocytes;creatinine ;uric acid;Anti-Sm Antibody;hematuria;Proteinuria; | — |
Countries
China
Contacts
Public ContactWang Meiying
Shenzhen Second People's Hospital
Outcome results
None listed