Comparison of short-term effectiveness of two different airway clearance techniques in hypersecretive critically ill patients: a randomized crossover study

Electrical impedance tomography was used to evaluate the lung ventilation and other physiological effects of two different airway clearance techniques in mechanically ventilated patients with airway hypersecretion

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087872

Enrollment

Unknown

Registered

2024-08-06

Start date

2024-03-01

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

High frequency chest wall oscillation group:Airway clearance was performed by High-frequency chest wall oscillation

Oscillation and Lung Expansion:Airway clearance was performed by Oscillation and Lung Expansion

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Age = 18 years ?Stay in ICU with mechanical ventilation duration =48h ?Fits the definition of airway hypersecretion(patients who required two or more broncoaspirations/hour in the previous 8h were considered "hypersecretive") ?Willing to sign informed consent

Exclusion criteria

Exclusion criteria: ?Malignant arrhythmia ?Acute myocardial ischemia ?Pneumothorax, pulmonary bulla and barotrauma and other lung diseases ?Hemorrhagic disease or abnormal coagulation mechanism with bleeding tendency ?Skin trauma on the chest ?pulmonary embolism ?Fitted with a permanent or temporary pacemaker ?Untreated spinal and rib fractures ?For any reasons, they could not be included in this study or the researchers considered it inappropriate to include this study.

Design outcomes

Primary

Measure	Time frame
end-expiratory lung impedance;Sputum PH;	—

Secondary

Measure	Time frame
tidal impedance variation;center of ventilation;global inhomogeneity;regional ventilation delay;heart rate;Blood oxygen saturation;Sputum weight;respiratory rate;	—

Countries

China

Contacts

Public ContactHongying Jiang

Beijing Rehabilitation Hospital of Capital Medical University

6jhy@163.com+86 139 1057 9176

Outcome results