mild cognitive impairment
Conditions
Interventions
Healthy control group:None
Sponsors
Shanghai Changning Mental Health Center
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: MCI patient group: Age range from 65 to 75 years old, meeting MCI diagnostic criteria: (1) Subjective examination with memory impairment; (2) Memory impairment with a course of = 3 months; (3) The score of the Montreal scale is between 15-24 points; (4) Does not meet the diagnostic criteria for dementia; (5) There is a decrease in self-care ability and social function; (6) Exclude cognitive impairment caused by special reasons. healthy control group: (1) Age range from 60 to 85 years old; (2) No cognitive impairment assessed by a specialist; (3) The MMSE score of 26-30 (4) does not meet any diagnostic criteria for dementia or MCI.
Exclusion criteria
Exclusion criteria: (1) Having severe physical and organic brain diseases; (2) Patients with mental illnesses such as schizophrenia and emotional disorders; (3) Abuse of alcohol or drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| P-tau217;P-tau181;Mont real Cognitive Assessmen t -Basic (MoCA-B); | — |
Secondary
| Measure | Time frame |
|---|---|
| Aß40;Aß42;NFL;Subjective Memory Complaints;HAMA;HAMD; | — |
Countries
China
Contacts
Public ContactLi Ting
Shanghai Changning Mental Health Center
Outcome results
None listed