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The Predictive Value of Shear Wave Elastography in Measuring Liver and Spleen Stiffness for Rebleeding in Esophageal and Gastric Varices

The Predictive Value of Shear Wave Elastography in Measuring Liver and Spleen Stiffness for Rebleeding in Esophageal and Gastric Varices

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087853
Enrollment
Unknown
Registered
2024-08-06
Start date
2024-08-17
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric and esophageal varices due to liver cirrhosis

Interventions

Gold Standard:Confirmed by endoscopy as bleeding due to rupture of esophageal and gastric fundal varices
Index test:Shear wave elastography for measuring liver and spleen stiffness

Sponsors

Zhengzhou University Affiliated Zhengzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with a confirmed diagnosis of cirrhosis based on clinical, laboratory, imaging, and/or pathological results; (2) Patients presenting with acute gastrointestinal bleeding, confirmed by endoscopy as esophageal variceal bleeding (EVB); (3) Patients who have undergone endoscopic treatment.

Exclusion criteria

Exclusion criteria: (1) Patients with primary liver cancer or other gastrointestinal malignancies, as these conditions or their treatments could cause gastrointestinal bleeding or affect the patients' survival; (2) Patients who have previously undergone transjugular intrahepatic portosystemic shunt (TIPS), splenic embolization, surgical splenectomy, and/or devascularization procedures for portal hypertension; (3) Patients with significant data missing or those lost to follow-up.

Design outcomes

Primary

MeasureTime frame
Liver stiffness;Spleen stiffness;Laboratory indicators;Sensitivity;Specificity;ROC curve;

Countries

China

Contacts

Public ContactYuanyuan Yan

Zhengzhou University Affiliated Zhengzhou Central Hospital

yanyuanyuan1974@126.com+86 187 0381 1997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026