Digestive system diseases
Conditions
Interventions
Group C:Remifentanil was injected intravenously with 0.2-0.4ug/kg (drug concentration 2ug/ml) for 30± 5 s, and was timed from the beginning. After 1 min, group C was injected intravenously with 0.2-0.
Group E:Remifentanil was injected intravenously with 0.2-0.4ug/kg (drug concentration 2ug/ml) and the infusion time was 30± 5 s. The infusion time was 30± 5 s from the beginning. After 1 min, etomidat
Sponsors
Yibin Second People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 60-80 years old. 2.ASA is graded from I to II. 3. Painless gastroscopy (within 20 minutes). 4.BMI:18~30kg/?. 5.Fried frailty Assessment Scale (?2 items).
Exclusion criteria
Exclusion criteria: 1. Patients and their families refused to participate in the study; 2. Allergic or contraindicated to opioids, cyclopofol, etomidate and other drugs and their components; 3. Patients with hypertension who did not receive formal antihypertensive treatment before surgery or whose blood pressure was poorly controlled [SBP= 160 mm Hg or =90 mm Hg, and/or DBP=100 mm Hg]; Preoperative BMI>30 or < 18 kg/?; Patients with severe anemia, hypotensive shock; 4. Patients with severe cardiopulmonary diseases, liver and kidney dysfunction, adrenal insufficiency, apnea syndrome, and modified Mallampati grade IV; 5. Patients with full stomach, digestive tract obstruction and progressive digestive tract bleeding; Recent use of antipsychotic drugs, drug abuse; 6. Patients with bronchial asthma, AECOPD, myasthenia gravis, severe mental illness, language and communication disorders; 7. Patients with a history of drug abuse, alcoholism, or drug addiction, and patients who have participated in other clinical trials as subjects within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of gastroscopy;Incidence of nausea and vomiting;Doctor and patient satisfaction evaluation;Incidence of muscle fibrillation;Success rate of gastroscopy insertion;Incidence of cough;Body motion rate;Incidence of sedation recovery;Incidence of injection pain; | — |
Countries
China
Contacts
Public Contactshen chunhong
Yibin Second People's Hospital
Outcome results
None listed