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Clinical study of sequential ablation and/or local SBRT radiotherapy after TACE in the unresectable hepatocellular carcinoma

Clinical study of sequential ablation and/or local SBRT radiotherapy after TACE in the unresectable hepatocellular carcinoma

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087832
Enrollment
Unknown
Registered
2024-08-05
Start date
2024-09-20
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Therapeutic Group:TACE combined with ablation and/or SBRT radiotherapy

Sponsors

Gaoxin Branch of The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: (1) Patients with hepatocellular carcinoma who are pathologically or meet clinical diagnostic criteria; (2) Patients with stage IIB-IIIB hepatocellular carcinoma; (3) Patients who have not been systematically treated with targeted therapy, immunotherapy, chemotherapy, etc.

Exclusion criteria

Exclusion criteria: (1) 80 years old; (2) Liver function Child grade C and B patients with >8 points; (3) Patients with severe cardiopulmonary, kidney and coagulation dysfunction; (4) Patients with history of esophageal and gastric varices bleeding; (5) pregnant women and patients with mental illness, or other conditions can not cooperate with the implementation of medical treatment;

Design outcomes

Primary

MeasureTime frame
Progression-free survival;The frequency and severity of adverse events;

Secondary

MeasureTime frame
Overall survival;Objective response rate;Disease control rate;

Countries

China

Contacts

Public ContactKe Fang

Gaoxin Branch of The First Affiliated Hospital of Nanchang University

fangkeqq88@163.com+86 138 7018 8644

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026