labor analgesia
Conditions
Interventions
sufentanil group:0.1%ropivacaine+0.3ug/ml sufentanil
Esketamine group:0.1%ropivacaine+0.3mg/ml Esketamine
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University, Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ASA I-II, 37-42 weeks of gestation, single pregnancy of primipara, age > 18.
Exclusion criteria
Exclusion criteria: 1. Patient refused. 2. Known allergy to lidocaine, ropivacaine and other local anesthesia drugs or other drugs in this test. 3.. Abnormal platelet or clotting function, abnormal liver or kidney function; 4. Previous cardiovascular, respiratory, nervous or psychiatric diseases; 5. Skin and soft tissue infection at the puncture site, or trauma, fracture, surgical history, lumbar disc herniation at the puncture site; 6. There are factors such as head basin imbalance, giant baby, twin pregnancy; 7. Participants deemed unsuitable for clinical trials by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset of analgesia time;proportion of breakthrough pain;PCA press times;Rescue analgesia times;1-min Apgar score;5-min Apgar score; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Heart rate;Blood pressure;fetal heart rate;Sensory block level;Bromage score;RSS score;Cesarean section rate;Analgesic dosage;Intrapartum hemorrhage;Complication;Neonatal outcome; | — |
Countries
China
Contacts
Public ContactZheng Shengxing
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed