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Adverse reactions of chemotherapy in cancer patients treated with intestinal microbiota transplantation

Adverse reactions of chemotherapy in cancer patients treated with intestinal microbiota transplantation

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087820
Enrollment
Unknown
Registered
2024-08-05
Start date
2023-12-18
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

Sponsors

Wuxi No.2 People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?=18 years old; (2) patients diagnosed with cancer and receiving chemotherapy; ? Systemic or local side effects caused by chemotherapy, such as nausea and vomiting, abdominal pain and diarrhea, hematochezia, etc. ? The patient had good liver and kidney function and immune system; (5) volunteer to participate in the study; ? conscious; ? They can communicate with each other normally.

Exclusion criteria

Exclusion criteria: ? Suffering from severe cardiovascular and cerebrovascular diseases, respiratory system diseases, immune system diseases and severe liver and kidney damage; ? suffering from severe mental illness, such as depression, generalized anxiety disorder, etc.; ? patients with intestinal infection or other infectious diseases; ? patients with allergic reactions to gut microbiota transplantation; ? patients who fail to provide complete medical history or examination data; ? Unable to carry out this study due to various reasons, various tests are needed; ? Fever, pregnancy, lactation, etc.; (8) Use of antibiotics in the past 2 weeks; ? Use of probiotics or immunomodulators in the past 1 month.

Design outcomes

Primary

MeasureTime frame
blood routine examination;hepatic and renal function;C-reactive protein;stool for routine;routine urianlysis;Amplification quantitative culture;mass spectrum identification;16S rRNA Sequence;metagenome;

Secondary

MeasureTime frame
glycosylated hemoglobin;blood fat;endotoxin;Infectious disease indicators;

Countries

China

Contacts

Public ContactFeng Ninghan

Wuxi No.2 People's Hospital

fnh888@njmu.edu.cn+86 138 1395 2696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026