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A randomized controlled trial of the effects of different blood flow rates on filter and circuit life in CRRT without anti-coagulation.

A randomized controlled trial of the effects of different blood flow rates on filter and circuit life in CRRT without anti-coagulation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087819
Enrollment
Unknown
Registered
2024-08-05
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

continuous renal replacement therapy

Interventions

Low blood flow rate group:150 mL/min for blood flow
Moderate blood flow rate group:200 mL/min for blood flow
High blood flow rate group:250 mL/min for blood flow

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Patients receiving CRRT; 2) Aged 18 and above; 3) No anticoagulant is used in the treatment of CRRT; 4) The patient himself or his legal guardian or agent provides informed consent.

Exclusion criteria

Exclusion criteria: 1) Patints receiving sufficent systemic anti-coagulation for other reasons (for example ECMO); 2) Patients unable to perform CRRT according to the pre-set blood flow rate due to vascular access dysfunciton; 3) Pregnant women.

Design outcomes

Primary

MeasureTime frame
CRRT filter and circuit life;—

Secondary

MeasureTime frame
Renal function;Blood pressure;Length of hospitalization;Survival status;Ventilation hours;—

Countries

China

Contacts

Public ContactZhao Yuliang

West China Hospital of Sichuan University

zhaoyuliang@scu.edu.cn+86 138 8080 1130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026