The mechanism of acupuncture treatment on cognitive impairment after stroke of phlegm turbidity and orifices

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087802

Enrollment

Unknown

Registered

2024-08-05

Start date

2024-08-12

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

stroke patient:acupunture therapy

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) met the diagnostic criteria for cognitive impairment after stroke in Western medicine and confirmed stroke by head CT or MRI; (2) Meet the diagnostic criteria of TCM stroke and dementia; (3) It meets the dialectical diagnosis standard of "phlegm, turbidity and enlightenment of traditional Chinese medicine"; (4) Right-handed hand, aged between 30 and 80 years old; (5) MMSE: 17 points for illiterate, 20 points for primary school, 24 points for middle school or above; (6) The MoCA is 20 points; (8) 7 points of TCM syndrome scale; (9) Patients with no complicated hematopoietic diseases, hemorrhagic diseases, diabetes mellitus, no severe infection, heart disease, malignant hypertension, epilepsy, Alzheimer's disease, or Parkinson's disease; no skin disease, rupture, or infection at the treatment site; (10) The patient's condition is stable, without consciousness disorder or mental symptoms, and he can cooperate with fNIRS examination and acupuncture treatment; (11) Those who meet the medical ethics norms, voluntarily join the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Previous Alzheimer's disease, history of brain trauma, tumor history or other central nervous system lesions and other diseases affecting cognitive function; (2) Patients with serious diseases of the heart, liver, kidney, lung and other organs or other major basic diseases that cannot be tolerated; (3) Long-term alcoholism or long-term use of cortical excitability-changing drugs (such as antidepressants, sedatives, etc.); (4) Severe hearing abnormalities, aphasia and other communication disorders, unable to complete the scale assessment or fNIRS examination task.

Design outcomes

Primary

Measure	Time frame
Cortical oxygenation with hemoglobin concentration;The MMSE Cognitive Scale;TCM syndrome integral scale;	—

Secondary

Measure	Time frame
The Montreal Cognitive Assessment Scale;	—

Countries

China

Contacts

Public ContactChen Fangyuan

The First Rehabilitation Hospital of Shanghai

386540717@qq.com+86 178 1023 4556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026