intraoperative esketamine
Conditions
Interventions
experimental group:esketamine
control group:saline
Sponsors
Xiangyang No.1 People's Hospital,Hubei University of Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective laparoscopic abdominal surgery; 2.Aged for 60-70 years; 3.BMI 18-30 Kg/m2; 4.ASA ?-? grade.
Exclusion criteria
Exclusion criteria: 1.patient refusal to participate in the study;2.body mass index higher than 30;3.preoperative Pittsburgh Sleep Quality Index (PSQI) higher than 7;4. recent history of drug abuse;5.contraindications or allergy to esketamine; 6.cognitive dysfunction or inability to communicate, and (7) inability to use a patient-controlled IV analgesia pump;8.The operation time of the patient was > 3 hours, or the laparotomy was switched.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative sleep quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Static and dynamic VAS score;adverse reaction;postoperative anxiety and depression score;expore the risk factors of sleep disturbance; | — |
Countries
China
Contacts
Public ContactHaijin Wang
Xiangyang No.1 People's Hospital,Hubei University of Medicin
Outcome results
None listed