A prospective clinical study of modified submandibular approach for tongue ablation combined with uvulopalatopharyngoplasty in the treatment of mild to moderate OSAHS

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087792

Enrollment

Unknown

Registered

2024-08-05

Start date

2024-08-15

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea hypopnea syndrome

Interventions

group One:Submandibular approach for tongue ablation combined with uvulopalatopharyngoplasty (UPPP)

group Two:Transoral tongue ablation combined with uvulopalatopharyngoplasty(UPPP)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: patients aged 18 to 70 years old, no gender limitation; Mild to moderate OSAHS; Palatine tonsils (Grade 1 or 2) ; Tongue hypertrophy (Grade III) ; No hypertrophy of lingual tonsil; No symptoms of nasal congestion; No mental illness or psychological disorder.

Exclusion criteria

Exclusion criteria: Acute inflammation of tongue and mandible skin; Abnormal coagulation function; a history of receiving tongue surgery; Tumors; Serious diseases related to heart, lung, liver and kidney, and autoimmune diseases; Patients who participated in other clinical trials one month ago; Patients who are considered unsuitable to participate in this clinical trial by the researchers.

Design outcomes

Primary

Measure	Time frame
Apnea Hyponea Index;	—

Secondary

Measure	Time frame
The lowest oxygen saturation;blood loss;Length of Stay;	—

Countries

China

Contacts

Public ContactJie Liu

The Sixth Affiliated Hospital of Sun Yat-sen University

liuj585@mail.sysu.edu.cn+86 136 3141 3972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026