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An observational study comparing expectant pregnancy and PGT-A pregnancy outcomes in patients with recurrent pregnancy loss

An observational study comparing expectant pregnancy and PGT-A pregnancy outcomes in patients with recurrent pregnancy loss

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087790
Enrollment
Unknown
Registered
2024-08-05
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Pregnancy Loss

Interventions

observation group :None.
control group :None.

Sponsors

Shengjing Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1) A history of spontaneous abortion or biochemical pregnancy before 24 weeks of pregnancy for =2 previous pregnancies; 2) The female was less than 40 years old at the time of entry; 3) Be able to understand informed consent and participate in this study voluntarily

Exclusion criteria

Exclusion criteria: 1)One or both spouses have a clear chromosomal karyotype abnormality or single gene disease; 2) Abnormal anatomical structure of the reproductive system: congenital uterine malformation, submucous myoma, uterine adhesiveness and after uterine adhesiveness, or before ovulation endometrial thickness <7mm, hydrosalpinx, endometriosis; 3) Patients with autoimmune diseases, antiphospholipid syndrome, thrombotic disease; 4) Hypertension, diabetes, heart disease, and endocrine diseases that are clearly not controlled within the normal range, such as abnormal thyroid function and prolactin; 5) Patients with malignant tumors; 6) Previously received PGT-A assisted pregnancy.

Design outcomes

Primary

MeasureTime frame
live birth rate;

Secondary

MeasureTime frame
chemical pregnancy rate;clinical pregnancy rate;miscarriage rate;multiple pregnancy rate;the rate of fetal defects;

Countries

China

Contacts

Public ContactShuyi Jiang

Shengjing Hospital of China Medical University

jiangshuyi@sj-hospital.org+86 189 4025 2798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026