Scar
Conditions
Interventions
Radiotherapy group:5 Gray*2 sessions (to be completed within 48h) of specified-dose superficial electron beam radiation therapy within 72h after surgery
Non-radiotherapy group:No special treatment for 72h after surgery
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 12 years and over 2. High-risk population 3. Incision is in a non-high-risk area** and the length of the incision is more than (including) 4cm 4. Skin type III/IV High-risk population: suspected possibility of pathological scarring, and/or history of pathological scarring, and/or family history of pathological scarring High-risk area: lower third of the face, shoulders, elbows, wrists, knees and ankles.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe skin diseases such as psoriasis, scleroderma, etc. 2. Clinically significant or unstable systemic diseases that are excluded on the basis of their potential to interfere with the safety profile of the study results, including malignant neoplasms, uncontrolled diabetes mellitus, uncontrolled hypertension, unstable pneumonitis, renal or hepatic organic disease, unstable myocardial ischaemic disease, dilated cardiomyopathy, myocardial conduction abnormalities, or unstable cardiovascular disease. etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of pathological scarring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient and Observer Scar Assessment Scale (POSAS) ;Security Indicators (adverse events); | — |
Countries
China
Contacts
Public ContactXiaoxi Lin
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed