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Effect of 2% lidocaine on nausea and vomiting after laparoscopic sleeve gastrectomy: a prospective, double-blind, randomized controlled trial

Effect of 2% lidocaine on nausea and vomiting after laparoscopic sleeve gastrectomy: a prospective, double-blind, randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087772
Enrollment
Unknown
Registered
2024-08-05
Start date
2024-08-10
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting, PONV

Interventions

Lidocaine group:During the operation, after the anterior and posterior gastric wall anastomosis was completed by the surgeon, 10ml of 2% lidocaine was sprayed on the surface of the stomach with a 10ml
Saline group:During the operation, after the anterior and posterior gastric wall anastomosis was completed by the surgeon, 10ml of saline was sprayed on the surface of the stomach with a 10ml syringe

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification grades I to III; 2. Female patients aged 18 - 65 years who undergo elective laparoscopic sleeve gastrectomy under general anesthesia; 3. The patients gave informed consent.

Exclusion criteria

Exclusion criteria: 1. History of drug allergy related to this study; 2. Coagulation dysfunction; 3. psychiatric or neurological diseases; 4. Communication difficulties; 5. Pre-use of antiemetics, opioids or glucocorticoids; 6. Suffer from gastroesophageal reflux disease; 7. Obese patients with severe heart, respiratory, kidney or liver disease.

Design outcomes

Primary

MeasureTime frame
Postoperative Nausea and Vomiting(PONV) rating scale;

Secondary

MeasureTime frame
Postoperative pain NRS(Numeric Rating Scale);Postoperative ?QoR-15(?Quality of Recovery-15) score;The time of the first use of rescue antiemetics;

Countries

CHina

Contacts

Public ContactLi Fuyuan

Fujian Medical University Union Hospital

460273860@qq.com+86 159 8053 6125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026