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Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Transabdominal and Extraperitoneal Pelvic Floor Reconstruction in the Treatment of Multisite Moderate to Severe Pelvic Organ Prolapse: A Prospective Randomized Controlled Study

Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Transabdominal and Extraperitoneal Pelvic Floor Reconstruction in the Treatment of Multisite Moderate to Severe Pelvic Organ Prolapse: A Prospective Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087770
Enrollment
Unknown
Registered
2024-08-05
Start date
2024-08-07
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pelvic organ prolapse

Interventions

one:extraperitoneal pelvic floor reconstruction
two:intraperitoneal pelvic floor reconstruction

Sponsors

The Obstetrics and Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with pelvic organ prolapse seeking treatment at the Obstetrics and Gynecology Hospital of Fudan University; (2) Female patients aged 50-80; (3) According to the POP-Q score, patients with at least one site at stage III or above, combined with at least one other site at stage II or above; (4) Patients who refuse conservative treatment or for whom conservative treatment has failed; (5) First-time pelvic organ prolapse surgery patients who desire surgical treatment and do not wish to preserve the uterus; (6) Patients may have concurrent urinary incontinence; (7) Patients willing to comply with regular postoperative follow-up.

Exclusion criteria

Exclusion criteria: (1) Patients who subjectively reject this surgical option; (2) Patients with a history of previous pelvic organ prolapse surgery; (3) Patients with a history of hysterectomy; (4) Patients with a strong desire to preserve the uterus; (5) Patients with severe medical or surgical diseases, tumors, infections, or bleeding; (6) Patients suspected or diagnosed with malignant pelvic tumors; (7) Patients who are too old to tolerate surgery.

Design outcomes

Primary

MeasureTime frame
Surgical success rate;

Secondary

MeasureTime frame
Anatomical recovery ;Functional recovery;Perioperative primary indicators;Mesh Complications;

Countries

china

Contacts

Public ContactYisong Chen

Obstetrics and Gynecology Hospital of Fudan University

cys373900207@163.com+86 136 0191 3713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026