chronic insomnia
Conditions
Interventions
RDPFC real group:The stimulation target was placed in the dorsolateral region of the right prefrontal lobe, 1x daily for 25min, 110% RMT, 1360 pulses, totally 4 weeks
R_PCC real group:The stimulation target is placed in the right posterior parietal lobe, 1x daily for 25min, 110% RMT, 1360 pulses, totally 4 weeks
Sham group:The stimulation target was placed in the dorsolateral region of the right prefrontal lobe or he right posterior parietal lobe
1x daily for 25min, 110% RMT, 1360 pulses, totally 4 weeks
Sponsors
Shenzhen People's Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. gender-neutral 2. right-handed 3. 30-50 years of age 30 50 years old; 4. meets the diagnostic criteria for insomnia in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5); 5. sleep disturbance occurs at least 3 nights per week and lasts for at least 3 months; 6. PSQI =7; 7. HAMD <20 and HAMA <21; 8. not currently taking insomnia-related medication and able to accept not taking insomnia medication during the period of enrolment; 9. able to complete the 1-month follow-up visit.
Exclusion criteria
Exclusion criteria: 1. concurrent comorbidity with depression, bipolar disorder, epilepsy, chronic pain, sleep apnea syndrome, restless legs syndrome and other diseases that may cause insomnia; 2. severe liver, kidney, cardiovascular, cerebrovascular, haematopoietic system diseases and their serious complications; 3. pregnant or breastfeeding women; 4. long term alcohol or drug abuse; 5. any contraindications to rTMS (including metal implanted in the body and devices such as pacemakers); 6. previous rTMS treatment within 1 year; 7. severe cognitive impairment, language impairment or inability to co-operate with treatment, MMSE <26 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index, PSQI;Insomnia Severity Index scores;MMSE scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale scores;Hamilton Anxiety Scale scores;Resting-state EEG features;TMS-EEG; | — |
Countries
China
Contacts
Public ContactGuo Yi
Shenzhen People's Hospital
Outcome results
None listed