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Impact of preoperative gut microbiota factors on postoperative intestinal injury in liver cancer patients undergoing laparoscopic hepatectomy with IPM

Impact of preoperative gut microbiota factors on postoperative intestinal injury in liver cancer patients undergoing laparoscopic hepatectomy with IPM

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087748
Enrollment
Unknown
Registered
2024-08-02
Start date
2024-08-02
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cancer

Interventions

Normal gastrointestinal function group:None
Postoperative gastrointestinal dysfunction group:None

Sponsors

Department of Anesthesiology, Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age = 18 years, = 70 years; (2) ECOG performance status score of 0-1; (3) Good cardiopulmonary function; (4) Patients with liver cancer scheduled for laparoscopic hepatectomy with IPM; (5) Able to comply with the study visit schedule and other protocol requirements; (6) Signed informed consent and voluntarily agreed to participate in this study.

Exclusion criteria

Exclusion criteria: (1) Obese patients (BMI > 30); (2) Patients with difficult intubation or expected complex airway management; (3) Patients with neurological dysfunction or who are unable to cooperate when awake; (4) Elderly and vulnerable patients with severe hypoxemia (PaO2 50/55 mmHg); (5) Patients deemed unsuitable based on clinical assessment; (6) Patients whose cardiopulmonary function or overall condition cannot tolerate the corresponding surgery; (7) Any medical or non-medical condition that the researcher deems unsuitable for participation; (8) Patients with preoperative intestinal diseases such as enteritis or those who have undergone intestinal surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative gastrointestinal function score ;Serum index: I-FABP;

Secondary

MeasureTime frame
Preoperative 1 day stool samples of gut microbiota;

Countries

China

Contacts

Public ContactDanfeng Wang

Department of Anesthesiology, Fujian Provincial Hospital

894898478@qq.com+86 139 0692 0551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026