biliary atresia
Conditions
Interventions
Gold Standard:The gold standard involves follow-up, surgical exploration and cholangiography when necessary. According to the gold standard, the postnatal outcome would be diagnosed as biliary atresia
Index test:The prenatal biliary imaging examination standards designed in the study, including prenatal ultrasound and magnetic resonance imaging examination. Details are provided in the study protoco
Sponsors
Children's Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: The fetuses whose prenatal imaging examinations are performed in seven cooperative hospitals in China according to the study protocol from August 05, 2024 to May 31, 2025, with guardians agreed with the study as well are included. The cooperative hospitals include Obstetrics and Gynecology Hospital of Fudan University, Shanghai First Maternity and Infant Hospital, International Peace Maternity and Child Health Hospital of China welfare institute, Shenzhen Maternity and Child Healthcare Hospital, Xiamen Maternal and Child Health Hospital, Nantong Maternal and Child Health Care Hospital, Shanghai Changning Maternity and Infant Health Hospital.
Exclusion criteria
Exclusion criteria: Termination of pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity;specificity;positive predictive value;negative predictive value;odds of being affected given a positive result; | — |
Secondary
| Measure | Time frame |
|---|---|
| Kappa value; | — |
Countries
China
Contacts
Public ContactShan Zheng
Children's Hospital of Fudan University
Outcome results
None listed