Perimenopausal central obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria of Perimenopausal Central Obesity; 2) Age between 40 and 60 years old; 3) Have not received weight loss treatment within 3 months; 4) Signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Secondary obesity: Hypothalamic syndrome, pituitary adenomas, Cushing's syndrome, hypothyroidism, insulinoma, polycystic ovary syndrome;2) Abnormalities of the uterus or ovaries, or individuals who have undergone hysterectomy or oophorectomy, as well as those who are pregnant or breastfeeding; 3) Comorbidities including hyperthyroidism, diabetes, malignant tumors, heart disease, liver disease, kidney disease, hematopoietic system disorders, mental illnesses, and other severe diseases; 4) No use of antibiotics, probiotics, or gastrointestinal motility drugs within the past 3 months; 5) Contraindications for magnetic resonance imaging (MRI); 6) Poor compliance, or other conditions not suitable for acupuncture and moxibustion treatment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Menopause-Specific Quality of Life;Kupperman Index;Triglycerides;Total cholesterol ;High-density lipoprotein cholesterol ;Fasting insulin;Fasting blood glucose;Follicle-stimulating hormone;Estradiol;Anti-Mullerian hormone ;The Homeostasis Model Assessment of Insulin Resistance ;Adiponectin;Intestinal flora;Features of brain function; | — |
Primary
| Measure | Time frame |
|---|---|
| Body weight;Body Mass Index;Waist circumference;Hip circumference;Waist-to-height ratio;Waist-to-hip ratio;Low-density lipoprotein ; | — |
Countries
China
Contacts
Zhejiang Hospital