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The study of the effect of dual-target iTBS on cognition and balance function in stroke patients based on fNIRS

The study of the effect of dual-target iTBS on cognition and balance function in stroke patients based on fNIRS

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087713
Enrollment
Unknown
Registered
2024-08-02
Start date
2024-08-10
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

CB-ITBS group:CB-ITBS
CB+DLPFC-iTBS group:CB+DLPFC-iTBS

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meet the stroke diagnostic criteria formulated by the Fourth National Conference on Cerebrovascular Diseases; (2) Stroke confirmed by CT or magnetic resonance imaging; (3) Age 18-75 years old; (4) It is the first disease; (5) Lateral subcortical stroke with contralateral limb paralysis as assessed; (6) The course of the disease is within 1 to 9 months; (7) can complete at least 10m walking with assistance; (8) The patient had certain balance disorders (Berg balance scale 10s); (9) MMSE (10 < score < 27) and MoCA (score < 26) screening showed cognitive dysfunction.

Exclusion criteria

Exclusion criteria: (1) non-first stroke; (2) frontal lobe injury; (3) Balance function and gait disorders caused by cerebellar, brain stem lesions or other diseases; (4) Have a history of epilepsy or family history; (5) Patients with metal implants or skull defects in the skull, with pacemakers and cochlear implants; (6) Attention deficit, unilateral neglect; (7) severe scalp dermatitis infection; (8) Patients were unable to complete the test due to various reasons during the test.

Design outcomes

Primary

MeasureTime frame
Berg Balance Scale;

Secondary

MeasureTime frame
the timed up and go test;Minimum Mental State Examination;Montreal Cognitive Assessment;Barycentric value, slope value and mean value of changes in oxygenated hemoglobin;motor evoked potential;

Countries

China

Contacts

Public ContactHuang Liping

Chinese PLA General Hospital

ping-online@163.com+86 133 9190 8450

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026