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Patient characteristics, treatment pattern and clinical outcomes of Diffuse Large B-Cell and Mantle Cell Lymphoma in China-PARADIGM

Patient characteristics, treatment pattern and clinical outcomes of Diffuse Large B-Cell and Mantle Cell Lymphoma in China-PARADIGM

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087712
Enrollment
Unknown
Registered
2024-08-02
Start date
2024-08-26
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diffuse Large B-Cell and Mantle Cell Lymphoma

Interventions

Sponsors

Beijing Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who meet the following criteria will be included in Cohort 1: • Patient had a confirmed diagnosis of DLBCL or ICD-10:C83. 3; • Patient was=18 years on the index date; • Patient received at least one regimen of lymphoma-related therapy between 1st July 2017 and 31st Dec 2022. (Lymphoma-related regimen including Systemic therapy, RT, HSCT) Patients who meet the following criteria will be included in Cohort 2: • Patient had a confirmed diagnosis of MCL or ICD- C83. 1; • Patient was=18 years on the index date; • Patient received at least one regimen of lymphoma-related therapy between 1st July 2017 and 31st Dec June 2022. (Lymphoma-related regimen including Systemic therapy, RT, HSCT)

Exclusion criteria

Exclusion criteria: • Patient has a minimal follow-up period less than six months; • Patients who took part in an interventional clinical trial for the treatment of DLBCL and MCL in first three lines of therapy. • Patient has received lymphoma-related MSD product/product class therapy during the eligibility period.

Design outcomes

Primary

MeasureTime frame
proportion of treatment regimens in DLBCL and MCL patients by line of therapies;proportion of BTKi usage in all patients by different patient characteristics;

Secondary

MeasureTime frame
real-world duration of treatment(rwDOT), real-world time to next treatment(rwTTNT), real-world progression-free survival (rwPFS), and Overall survival (OS) by lines of therapy ;

Countries

China

Contacts

Public ContactYuqin Song

Beijing Cancer Hospital

songyuqin622@163.com+86 10 8819 6118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026