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The impact of nutritional interventions on quality of life in patients undergoing radiotherapy for nasopharyngeal carcinoma based on dynamic nutritional risk screening and assessment: A randomized controlled trial

Impact of Dynamic Nutritional Risk Screening and Assessment on Quality of Life of Patients with Head & Neck Cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087710
Enrollment
Unknown
Registered
2024-08-02
Start date
2022-03-04
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal Carcinoma

Interventions

Intervention Group:Provide individualized nutritional support based on nutritional assessment results, reassess nutritional status and acute radiation-induced oral mucositis weekly, and adjust dietary
Control Group:Patients are fed according to their appetites and desires and are not provided with additional intensive nutritional counseling or education recommendations.

Sponsors

Jiangxi Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Histopathologically confirmed diagnosis of nasopharyngeal carcinoma; 2. Patients who will receive primary radiotherapy at our hospital; 3. Aged 18-75 years 4. Have a Karnofsky Performance Status (KPS) score of =70; 5. Have no significant hepatic or renal disease, cardiopulmonary dysfunction, or severe endocrine or metabolic disease that would interfere with the patient's ability to receive primary radiotherapy; 6. Be able to communicate in normal language or writing; 7. Be willing to cooperate with the researchers in the assessment of nutritional status and quality of life, and comply with the requirements of the study; 8. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who have undergone radiotherapy for nasopharyngeal carcinoma ; 2. Having distant metastasis; 3. With mental illness, intellectual disability, or other physical or psychological disorders that may lead to cognitive dysfunction; 4. Pregnant or lactating patients.

Design outcomes

Primary

MeasureTime frame
Dynamic quality of life ;

Secondary

MeasureTime frame
Dynamic nutritional status ;Progression-free survival (PFS) and overall survival (OS) at 1-5 years;

Countries

China

Contacts

Public ContactChunhong Guan

Jiangxi Cancer Hospital

guan_chunhong@163.com+86 139 7099 2690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026