thyroid disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Elective thyroidectomy; ? Age of 18-60 years old; ?BMI18-30kg/m2. ? American Society of Anesthesiologists score ?-?.
Exclusion criteria
Exclusion criteria: ? Previous allergies to the drugs used in this study; (2) long-term use of alcohol or sedative drugs; (3) preoperative analgesic drugs; ? previous neuropsychiatric disorders, coma, depression, cognitive impairment; ?SBP<85mmHg or HR<50 bpm/min; 6. Refused to participate in this study; ? Acute upper respiratory tract disease, liver and kidney failure, severe heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50 and ED95 of sufentanil required for induction of anesthesia in patients with different sensitivity groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scale score, VAS;Incidence of nausea and vomiting; | — |
Countries
China
Contacts
The Second Hospital of Hebei Medical University