High grade squamous intraepithelial leasion
Conditions
Interventions
Case series:None
Sponsors
The Second Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
Female
Age
25 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients voluntarily participated in the study and signed informed consent; 2. Female patients aged =25 years old and =64 years old; 3. Abnormal cervical cytology (=AS-CUS) and/or abnormal cervical biopsy pathology within 30 days before screening; 4. No contraindications to vaginal sampling and urine sampling; 5. Willingness to collect urine, vaginal discharge and cervical exfoliated cell samples; 6. Not participating in other clinical studies within 30 days before screening.
Exclusion criteria
Exclusion criteria: 1. Previous cervical cytology > 30 days without recent results; 2. Patients received cervical physical therapy, LEEP, cervical conization, and cervical amputation due to abnormal results of cervical cancer screening before screening; 3. Patients with acute vaginal inflammation are not suitable for vaginal sampling; 4. Those who are already pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High grade squamous intraepithelial leasion; | — |
Secondary
| Measure | Time frame |
|---|---|
| HPV genotype;Gene methylation; | — |
Countries
China
Contacts
Public ContactWuliang Wang
The Second Affiliated Hospital of Zhengzhou University
Outcome results
None listed