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Effects of dexmedetomidine and propofol on postoperative oxygenation index in patients undergoing coronary artery transplant: A single-centre retrospective study

Effects of dexmedetomidine and propofol on postoperative oxygenation index in patients undergoing coronary artery transplant: A single-centre retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087672
Enrollment
Unknown
Registered
2024-08-01
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Group D:None
Group P:None

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing coronary artery bypass grafting under general anesthesia; 2. Aged 60 to 75 years old; 3. ASA grading III-IV; 4. During postoperative mechanical ventilation, only propofol or dexmedetomidine should be used for sedation.

Exclusion criteria

Exclusion criteria: 1. Preoperative cognitive impairment; 2. Severe respiratory system disease; 3. Severe liver and kidney dysfunction; 4. Recent use of antidepressants, sedatives, or analgesics; 5. History of drug allergy in research; 6. History of previous chest surgery; 7. Incomplete perioperative data; 8. Other factors considered to have an impact on the results of this study.

Design outcomes

Primary

MeasureTime frame
Oxygenation index;—

Secondary

MeasureTime frame
Mean arterial pressure, MAP;heart rate, HR;Extubation time;—

Countries

China

Contacts

Public ContactLuwei Ma

Shandong Provincial Hospital

mlw2022@126.com+86 151 6515 6952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026