Retinal disease
Conditions
Interventions
Gold Standard:magnetic resonance imaging. When cerebral small vessel lesions are secondary to a variety of brain tissue damage, they can be identified by neuroradiology, and the prominent manifestatio
Index test:Optical Coherence Tomography Angiography. The recruited patients were scanned by Angio-OCT to accurately locate and scan the macular area and the key areas of the optic nerve, and the retin
Sponsors
Ruijin Hospital Luwan Branch
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Cerebral small vessel disease (CSVD) group: The diagnosis of CSVD is mainly based on brain imaging markers, which can be identified by neuroradiology when vascular lesions cause multiple brain tissue injuries. CSVD is characterized by prominent imaging features such as cavities, white matter lesions, cerebral microbleeds, and enlargement of perivascular spaces. Standardized diagnosis based on clinical manifestations and imaging examinations. Control group: a normal population matched in age with the cerebral small vessel disease group. The experimental group and the control group had no history of other eye diseases or surgeries, and their pupils moved freely without adhesions. Those who can fully understand the research purpose, research content, accidents, benefits and risks of the clinical study, and can make their own decisions about whether to participate or not to participate. Those who voluntarily participate in the research of this project and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with corneal lesions, uveitis, vitreous-related diseases, history of ocular surgery and systemic diseases that may lead to ocular complications, history of other retinopathy presence or treatment, and poor general condition that makes it difficult to cooperate with the examination. (2) Participated in clinical trials of intraocular or systemic drugs in the past 6 months. (3) Other unqualified conditions determined by the investigator, including but not limited to nystagmus, inability to fix vision and other reasons that cannot complete the normal examination. (4) Those with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optical Coherence Tomography Angiography;AUC;ROC Curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Avoid dilated pupils and wide-angle fundus photography;Magnetic Resonance Imaging;accuracy;sensitivity;specificity; | — |
Countries
China
Contacts
Public ContactYu Zhou
Ruijin Hospital Luwan Branch
Outcome results
None listed