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A randomized controlled trial of abdominal acupuncture combined with repetitive transcranial magnetic stimulation for the treatment of post-stroke cognitive impairment and modulation of intestinal flora

A randomized controlled trial of abdominal acupuncture combined with repetitive transcranial magnetic stimulation for the treatment of post-stroke cognitive impairment and modulation of intestinal flora

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087654
Enrollment
Unknown
Registered
2024-07-31
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post stroke cognitive impairment

Interventions

observation group:acupuncture and repetitive transcranial magnetic stimulation
comparison group:Repetitive transcranial magnetic stimulation

Sponsors

Jiaxing Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. meet the diagnostic criteria for stroke and post-stroke cognitive impairment; 2. aged 45-75 years old, conscious and with stable vital signs; 3. Minimum Mental State Examination (MMSE) [31]: illiterate =17 points, elementary school =20 points, middle school and above =24 points. Montreal Cognitive Assessment (MOCA)[32]: illiterate group =19 points, elementary school group =22 points, middle school and above group =24 points; 4. Patients without visual, hearing, intellectual or speech disorders; 5. patients receiving treatment under this protocol, informed and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. a history of cognitive decompensation prior to the current onset of the disease; 2. Combination of Alzheimer's disease, brain tumor, traumatic brain injury, etc. which can lead to cognitive decompensation; 3. people with severe hepatic or renal insufficiency; 4. Pregnant or lactating women; 5. Those who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Mini-mental State Examination;

Secondary

MeasureTime frame
Montreal Cognitive Assessment;Modified Barthel Index;National Institute of Health stroke scale;Pittsburgh sleep quality index;Hamilton Anxiety Scale;Hamilton Depression Scale;

Countries

China

Contacts

Public ContactYanlin Liu

Jiaxing Hospital of Traditional Chinese Medicine

liuyanlin2193@163.com+86 189 4510 4116

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026