Chronic postoperative pain
Conditions
Interventions
Bupivacaine liposome group:20 mL 266 mg bupivacaine liposomes+10 mL 0.9% physiological saline
Bupivacaine group:0.5% bupivacaine hydrochloride 30 mL
Sponsors
The Second Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo thoracoscopic partial lung resection under general anesthesia (lung wedge, segment, lobe); 2. Age = 18 years old; 3. BMI index 18-30kg/?; 4. ASA level I to II; 5. Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Refuse to participate in this study; 2. Communication barriers, inability to cooperate with researchers, such as language comprehension disorders, mental illness, epilepsy, history of Parkinson's disease, or myasthenia gravis; 3. Identify/suspect individuals with a history of alcohol, analgesics, or other substance abuse and addiction; 4. Individuals who are allergic to the drugs used in this study; 5. Long term chronic pain before surgery; 6. Previous history of chest surgery; 7. The supervising doctor or researcher believes that there are other situations that are not suitable for participation in this study (reasons need to be recorded).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic pain three months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative acute pain incidence rate;Pain incidence rate one month after surgery;Pain incidence rate at six months after surgery;Postoperative use of PCIA;Postoperative analgesic medication usage;Postoperative nausea and vomiting incidence;Postoperative incidence of pulmonary complications;Postoperative drainage tube retention status;Hospitalization days;Perioperative inflammatory factor indicators; | — |
Countries
China
Contacts
Public ContactChangjun Gao
The Second Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed