Anesthesiology
Conditions
Interventions
Bupivacaine hydrochloride and bupivacaine liposome mixture group:a mixture of bupivacaine hydrochlorideand bupivacaine liposomes
Bupivacaine hydrochloride group:bupivacaine hydrochloride
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years old. 2. ASA I-III. 3. Those scheduled to undergo breast cancer surgery under intubation general anesthesia. 4. Those sent to PACU for resuscitation after surgery.
Exclusion criteria
Exclusion criteria: 1.Patients with difficult airway; 2.Patients with cardiac, hepatic and renal dysfunction; 3.Patients with allergy to study medications; 4.Patients with respiratory tract infection in the last two weeks; 5.Patients withinfection at the point of needle entry; 6.Patients with severe anemia, shock, metabolic disease, electrolyte disorders; 7.Patients with gastric retention or delayed gastric emptying. 8.Communication barriers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-mastectomy pain syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Exercise versus resting VAS pain scores upon leaving the PACU, postoperative (1 day, 2 days, 3 days);Vital signs(blood pressure, HR, SpO2, RR, BIS);Total vasoactive drug use;Total anesthetic drugs;Surgical time, anesthesia time, awakening time;Comfort Evaluation;Preoperative anxiety score;Dosage of analgesics at 1, 2, and 3 days postoperatively;Duration of sensory block in patients; | — |
Countries
China
Contacts
Public ContactXuehai Guan
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed