Oral candidiasis
Conditions
Interventions
oral candidiasis group:none
control group:none
Sponsors
Peking University School and Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: (1) Case group: Inclusion criteria: 1) Clinical diagnosis of oral candidiasis; 2) Microscopic examination detected Candida hyphae or salivary Candida culture identified Candida spp. 3) Whole genome exome sequencing to detect pathogenic gene mutations; 4) voluntary participation and written informed consent signed by the subjects. (2) Control group: Inclusion criteria: 1) Patients with a clinical diagnosis of a hyperplasia or pigmented nevus of the tongue and whose treatment plan is surgical excision; 2) Subjects voluntarily participated and signed a written informed consent.
Exclusion criteria
Exclusion criteria: (1) Case group: 1)Those who had received systemic antifungal medication within 30 days or topical antifungal medication within 2 weeks prior to the visit; 2) Unwilling participants. (2) Control group: 1) Those with contraindications to surgery; 2) Unwilling participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Screening for genetic mutations;Peripheral Blood Cytokine Testing;Tissue single-cell sequencing; | — |
Countries
China
Contacts
Public ContactPeiru Zhou
Peking University School and Hospital of Stomatology
Outcome results
None listed