Chronic kidney disease
Conditions
Interventions
Healthy control group:none
Sponsors
the Affiliated Wuxi People's Hospital to Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Control group: Some patients' family members require good health and no underlying diseases. CKD: group 1.Patients with Stage 3-5 chronic kidney disease (eGFR <60ml/min·1.73m2) 2.Age ranges from 18 to 80 years old 3.Stable and conscious 4. All patients and their families were aware of the study content and signed informed consent.
Exclusion criteria
Exclusion criteria: 1.The primary diseases were systemic lupus erythematosus, vasculitis, autoimmune diseases combined with malignant tumors, end-stage liver disease and chronic intestinal diseases. 2.Patients are taking hormones and immunosuppressants 3.Patients had thyroid disease, acute and chronic infection, acute cardiovascular events in the last 1 month 4.Oral antibiotics, probiotics, prebiotics and other drugs in the past 1 month 5. Long-term bedridden patients unable to feed themselves 6.Patients with mental disorders affecting treatment compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatinine;Serum urea nitrogen;Serum albumin;hemoglobin;gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum calcium;Serum phosphorus;Serum metabolites;Fecal metabolites;Peritoneal dialysis fluid inflammatory factors;Urine metabolites;24 hour urine protein;24 hours urinary creatinine;24 hours urea nitrogen;Peritoneal dialysis fluid metabolites; | — |
Countries
China
Contacts
Public ContactLiang Wang
The Affiliated Wuxi People's Hospital to Nanjing Medical University
Outcome results
None listed