vaginal intraepithelial neoplasia
Conditions
Interventions
Sponsors
International Peace Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 25-65 years who are diagnosed as high-risk HPV positive by HPV genotyping test; 2) Patients with VAIN (including VAINI/II/III) confirmed by colposcopy-guided histopathological biopsy of vaginal wall biopsy; 3) Patients who have not received any other treatment within the previous 2 years.
Exclusion criteria
Exclusion criteria: 1) Patients whose cytological and histological examinations show malignant cells or suspected cancerous changes and cancerous infiltration; 2) Patients with severe pelvic inflammatory disease, cervicitis, vaginitis, or other severe gynecological inflammation found in clinical examination; 3) Patients with undiagnosed vaginal bleeding; 4) Patients with allergy to drugs used in this study or known porphyria; 5) Pregnancy or breastfeeding; 6) Patients with severe organic diseases, psychiatric disorders, autoimmune diseases or immunosuppression. 7) Patients with a combination of other systemic malignancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lesion clearance; | — |
Secondary
| Measure | Time frame |
|---|---|
| HPV clearance; | — |
Countries
China
Contacts
Public ContactDan Wu
International Peace Maternity and Child Health Hospital
Outcome results
None listed