Diabetes with osteoporosis
Conditions
Interventions
Experimental group:Gushuling+Calcium Carbonate D3 Tablets+Alendronate Sodium Tablets
Control group:Calcium Carbonate D3 Tablets+Alendronate Sodium Tablets
Sponsors
The First Affiliated Hospital of Anhui University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) At the same time, it meets the diagnostic criteria of diabetes and osteoporosis; 2) Not taking hormone drugs or anti osteoporosis drugs in the past 3 months; 3) Stop all other interventions for this disease; 4) Fasting blood glucose and 2-hour postprandial blood glucose control are stable (fasting blood glucose is controlled between 5-7.5mmol/L, and postprandial blood glucose is controlled within 11.1mmol/L) 5) Patients who do not agree to sign the informed consent form for this study.
Exclusion criteria
Exclusion criteria: 1) Patients with combined diseases such as adrenal, thyroid, kidney, severe cardiovascular disease, or liver and kidney dysfunction; 2) Individuals who are allergic to the use of drugs in this study; 3) Osteoporosis accompanied by one or more bones that require surgical treatment; 4) Those who are not suitable for treatment due to chronic digestive tract diseases and inconvenience in movement; 5) Esophageal abnormalities leading to esophageal emptying disorders and other conditions; 6) Patients with hypocalcemia; 7) Patients with metabolic and rheumatic diseases that affect bone metabolism, or those who take drugs that affect bone metabolism for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density (lumbar spine); | — |
Secondary
| Measure | Time frame |
|---|---|
| Ca P ALP 25(OH) D3 ß-CTx OPG Foxo1 PTGS2;Blood glucose levels: (fasting blood glucose, 2-hour postprandial blood glucose); | — |
Countries
China
Contacts
Public ContactYang Mao
The First Affiliated Hospital of Anhui University of Chinese Medicine
Outcome results
None listed