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Pathogenesis of phlegm-stasis interjunction type of ischemic stroke And an exploratory study of the mechanism of Xingnaojieyu capsule

Pathogenesis of phlegm-stasis interjunction type of ischemic stroke And an exploratory study of the mechanism of Xingnaojieyu capsule

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087527
Enrollment
Unknown
Registered
2024-07-29
Start date
2024-04-18
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Treatment group:drug therapy.The patient took 5 capsules/day for 3 months.
Control group:None

Sponsors

Affiliated Hospital of Shaanxi University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patient enrollment criteria: (1) Meet the diagnostic criteria for acute phase of ischemic stroke; (2) National Institutes of Health Stroke Scale (NIHSS score) : 1 point =NIHSS < 15 points; (3) Ischemic stroke patients who meet the TCM syndrome differentiation as phlegm-stasis interjunction type; (4) Stroke was confirmed by MRI or craniocerebral CT. (5) Age between 40 and 80 years old, gender is not limited; (6) Patients and their families were aware of the general situation of this study and voluntarily signed informed consent. Control group admission criteria: (1) No special medical history, no abnormal findings in physical examination; (2) No history of infection in the past 2 months.

Exclusion criteria

Exclusion criteria: (1) Ischemic stroke caused by brain injury, liver and kidney insufficiency, heart insufficiency, immune deficiency, blood disease, hereditary vascular disease, drug abuse and other diseases; (2) Patients with severe cardiovascular, liver, kidney, hematopoietic and endocrine and immune system diseases; (3) Patients with mental disorders or mental disorders; (4) Cancer and tumor patients; (5)Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
5-LOX;LTB4;TNF-a;IL-6;TC;TG;HDL-C;LDL-C;NIHSS;HAMD-17;

Secondary

MeasureTime frame
hs-CRP;Hcy;APTT;PT;FIB;TCM syndrome score scale;

Countries

China

Contacts

Public ContactBin Wang

Shaanxi University of Chinese Medicine

wangbin812@126.com+86 138 9298 1087

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026