Osteoarthritis of the knee
Conditions
Interventions
intervention group:Intraoperative low-dose intravenous pumping of dexmedetomidine combined adductor canal block
control group:Intraoperative low-dose intravenous saline pumping combined sham block
Sponsors
Provincial Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients requiring unilateral initial TKA surgery; 2. Age: 65~80 years old; 3. Body mass index:18~35 kg/m2; 4. The American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level; 5. The patient signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. other surgeries on the same knee; 2. allergy to the drugs used in this study or opioid abuse; 3. contraindications to nerve block; 4. infection at the puncture site; 5. coagulation disorders; 6. severe cardiac, cerebral, hepatic, renal, and central nervous system disorders; 7. communication disorders; 8. planned admission to the ICU after the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour postoperative Quality of Recovery 15-item scale score (QoR-15); | — |
Secondary
| Measure | Time frame |
|---|---|
| 48-hour postoperative Quality of Recovery 15-item scale score (QoR-15);Visual analogue score;Time to first postoperative rescue analgesia;Hemodynamics;The total amount of rescue analgesic drugs was used 24 hours after surgery;Pittsburgh Sleep Quality Score; | — |
Countries
China
Contacts
Public ContactWang Gongming
Provincial Hospital of Shandong First Medical University
Outcome results
None listed