A prospective observational study on the treatment of early-stage non-small cell lung cancer with predominant ground-glass opacity components in cT1N0 by segmentectomy.

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400087523

Enrollment

Unknown

Registered

2024-07-29

Start date

2024-07-31

Completion date

Unknown

Last updated

2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Segmentectomy group:This study is a single-arm, multicenter, prospective, observational study, where all tests, examinations, and surgical protocols are part of the standard diagnostic and treatment p

if the lymph nodes are positive or the margin is not met, the procedure is changed to lobectomy.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Chest CT meets all of the following criteria: a. Suspected lung cancer (excluding the middle lobe) b. N0 c. T = 3cm; C/T = 0.5 d. Three-dimensional reconstruction shows the tumor center is located in the middle one-third of the lung field, that is, the distance from the second carina to the tumor center / the distance from the second carina to the pleural surface is less than 2/3 e. Planned resection margin on three-dimensional reconstruction: ensuring the margin is greater than 2cm or equal to the tumor diameter 2. The number of additional nodules is less than 2, and the additional nodules meet the following: a. T = 2cm; C/T < 0.25 and located in the outer one-third of the lung field b. Pure ground-glass opacity (GGO) and = 1cm 3. R0 resection

Exclusion criteria

Exclusion criteria: 1. History of other malignant tumors within the last 5 years, except for in situ or mucosal tumors. 2. Concurrent interstitial pneumonia, pulmonary fibrosis, or severe COPD (Chronic Obstructive Pulmonary Disease). 3. Any unstable systemic disease: uncontrollable hypertension, unstable angina, congestive heart failure, myocardial infarction within the past six months, severe arrhythmia, liver, kidney, or metabolic disorders. 4. Pregnancy, planning to become pregnant, or breastfeeding. 5. Mental illness. 6. Infections that are difficult to control. 7. Any other conditions deemed unsuitable for enrollment by the investigator.

Design outcomes

Primary

Measure	Time frame
Disease free survival ;	—

Secondary

Measure	Time frame
Perioperative complications ;Lung function post surgery;	—

Countries

China

Contacts

Public ContactWang Shaodong

Peking University People's Hospital

13651217347@163.com+86 136 5121 7347

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026